Cannabis Hyperemesis Syndrome: Causes, Treatment, and More

Cannabis Hyperemesis Syndrome: Causes, Treatment, and More

cannabinoid hyperemesis syndrome death

They may also prescribe antipsychotic medications such as haloperidol (Haldol) or olanzapine (Zyprexa) to help you calm down as you switch to the recovery phase. Researchers aren’t sure exactly why weed causes CHS symptoms only in some people. The researchers found that 32.9 percent of the participants reported having experienced symptoms of CHS in the past.

A paradoxical condition

Knowledge of pharmacological treatments for managing CHS may lessen the burden of ED resources with the recurring admission of patients with CHS [20, 23, 25, 28, 31, 33, 35]. The third phase is the recovery phase, which is a return to normal behavior. With the changing climate of marijuana laws, it is an important condition to consider when establishing a differential.

Unveiling the Therapeutic Potential of Hot Showers in CHS Symptom Management

cannabinoid hyperemesis syndrome death

Brian was also experiencing symptoms even after he had quit smoking, which caused us to doubt the diagnosis further. We had never heard of marijuana causing nausea or vomiting and were only familiar with its various health benefits, so we did not believe that CHS was what Brian had. Vital signs were significant for mild hypertension (150/75), but the patient was afebrile with a normal heart rate.

cannabinoid hyperemesis syndrome death

Help quitting cannabis

cannabinoid hyperemesis syndrome death

They rushed to the St. Francis emergency room, where doctors transferred him to Riley Hospital for Children. She knew he was not going to give up smoking, but she thought being around his nephew would encourage him to smoke less. The best treatment for CHS is to stop using cannabis entirely, Habboushe said. Denney remained unconvinced, thinking the specialist was too quick to accept the emergency room doctor’s diagnosis without doing any confirmatory testing. Although neither Denney nor Brian accepted the diagnosis completely, she urged him to consider not smoking as a process of elimination.

  • Synthetic cannabinoids are the most abused synthetic drug and second most abused drug among adolescents.
  • The reason why I know so much about this is that it happened to my son.
  • Drugs with an anticholinergic effect may likewise block medullary mediated vomiting, though they may have minimal impact on visceral stimulation, including the crippling abdominal cramping pain that patients with CHS experience.
  • It would seem that persistent use of marijuana should provoke persistent or at least protracted symptoms, but nearly all CHS patients report long asymptomatic breaks between relatively short symptomatic episodes while they continue to use marijuana.
  • Marijuana cessation relieves CHS, sometimes in a matter of hours or a couple of days.

cannabinoid hyperemesis syndrome death

Through a holistic and individualized treatment regimen, healthcare providers can navigate the challenges of CHS, offering hope and relief to those affected by this puzzling condition. Doctors don’t yet know how the illness forms or why it affects a small segment of pot consumers. Doctors believe that genes may play a role and that an over-accumulation of cannabis in the body may create a harmful reaction in the same areas — the brain’s hypothalamus, serotonin levels, or receptors — that marijuana, in small doses, may act on to reduce nausea. THC crosses the placenta and can accumulate in significantly elevated concentrations in breast milk. The hepatic cytochrome p450 system primarily metabolizes THC to many metabolites, mostly inactive.

cannabinoid hyperemesis syndrome death

Conclusions made were limited due to the low-quality of available evidence. Additionally, some of the statistically significant studies did not measure symptom relief, instead looked cannabinoid hyperemesis syndrome at the reduced LOS in hospitals [23, 24, 25, 28, 31]. Furthermore, LOS in the ED was used to measure the stabilization of N/V symptoms; however, it was not a marker of CHS cure.

  • The data that support the findings of the present study are available on request from the corresponding author.
  • On her dresser sits a dark urn emblazoned with a gold marijuana leaf that contain’s Brian’s ashes.
  • An 18-year-old patient diagnosed with CHS refused to stop using marijuana and was treated in-clinic with haloperidol followed by outpatient 5 mg haloperidol which relieved her symptoms of nausea and vomiting.
  • Along with the discovery of the CB1 and CB2 receptors has been the identification of endogenous arachidonic acid derivatives that bind to these receptors (Figure 1).

Supportive Care with Fluid and Electrolyte Replacement

No Comments

Post A Comment